The 100 percent non-smoking Comfort Inn & Suites Near Medical Center is ideally located off Interstate 10, less than five miles from the San Antonio International Airport. This San Antonio, TX hotel is minutes from the San Antonio Zoo and Aquarium, the Alamodome multipurpose venue, SeaWorld San Antonio theme park, Six Flags Fiesta Texas amusement park, the historic Alamo landmark and museum and the world-famous San Antonio River Walk.The surrounding area offers guests a variety of activities. Spend the day golfing on one of San Antonio's pristine 18-hole courses. Find that must-have item at one of the nearby shopping centers and explore the charming galleries filled with local treasure. There are restaurants and cocktail lounges close by to suit every taste and appetite from elegant to casual.